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Department of Geriatrics
References
- Ahn JD, Morishita R, Kaneda Y, Lee SJ, Kwon KY, Choi SY, Lee KU, Park JY,
Moon IJ, Park JG, Yoshizumi M, Ouchi Y, Lee IK: Inhibitory effects of novel
AP-1 decoy oligodeoxynucleotides on vascular smooth muscle cell
proliferation in vitro and neointimal formation in vivo. Circ Res 90:
1325-1332, 2002
- Akishita M, Toba K, Nagano K, Ouchi Y: Adverse drug reactions in older
people with dementia. J Am Geriatr Soc 50: 400-401, 2002
- Ako J, Kozaki K, Yoshizumi M, Ouchi Y: Transient left ventricular apical
ballooning without coronary artery stenosis: a form of stunning-like
phenomenon? J Am Coll Cardiol 39: 741-742, 2002
- Aoki-Nagase T, Nagase T, Oh-Hashi Y, Shindo T, Kurihara Y, Yamaguchi Y,
Yamamoto H, Tomita T, Ohga E, Nagai R, Kurihara H, Ouchi Y: Attenuation of
antigen-induced airway hyperresponsiveness in CGRP-deficient mice. Am J
Physiol Lung Cell Mol Physiol 283: L963-970, 2002
- Amiya E, Ako J, Kozaki K, Iijima K, Nagase T, Ouchi Y: Yellow nail
syndrome in an elderly man. Geriat Gerontol Int 2: 157-160, 2002
- Cosentino F, Bonetti S, Rehorik R, Eto M, Werner-Felmayer G, Volpe M,
Luscher TF: Nitric-oxide-mediated relaxations in salt-induced hypertension:
effect of chronic beta1 -selective receptor blockade. J Hypertens 20:
421-428, 2002
- Eto M, Kozai T, Cosentino F, Joch H, Luscher TF. Statin prevents tissue
factor expression in human endothelial cells: role of Rho/Rho-kinase and Akt
pathways. Circulation 105: 1756-1759, 2002
- Fujita M, Ogawa S, Fukuoka H, Tsukui T, Nemoto N, Tsutsumi O, Ouchi Y,
Inoue S: Differential expression of secreted frizzled related protein 4
(sFRP4) in decidual cells during pregnancy. J Mol Endocrinol 28: 213-223,
2002
- Fujita M, Urano T, Horie K, Ikeda K, Tsukui T, Fukuoka H, Tsutsui O,
Ouchi Y, Inoue S: Estrogen activates cyclin-dependent kinases 4 and 6
through induction of cyclin D in rat primary osteoblasts. Biochem Biophys
Res Commun 299: 222-228, 2002
- Hashimoto M, Miyao M, Akishita M, Hosoi T, Toba K, Kozaki K, Yoshizumi
M, Ouchi Y: Effects of long-term and reduced-dose hormone replacement
therapy on endothelial function and intima-media thickness in postmenopausal
women. Menopause 9: 58-64, 2002
- Iijima K, Yoshizumi M, Ouchi Y: Effect of red wine polyphenols on
vascular smooth muscle cell function--molecular mechanism of the 'French
paradox'. Mech Ageing Dev 123: 1033-1039, 2002
- Iijima K, Yoshizumi M, Hashimoto M, Akishita M, Kozaki K, Ako J,
Watanabe T, Ohike Y, Son B, Yu J, Nakahara K, Ouchi Y: Red wine polyphenols
inhibit vascular smooth muscle cell migration through two distinct signaling
pathways. Circulation 105: 2404-2410, 2002
- Jin GB, Hong T, Inoue S, Urano T, Cho S, Otsu K, Kitahara M, Ouchi Y,
Cyong JC: Augmentation of immune cell activity against tumor cells by
Rauwolfia radix. J Ethnopharmacol 81: 365-372, 2002
- Jin GB, Inoue S, Urano T, Cho S, Ouchi Y, Cyong JC: Induction of anti-metallothionein
antibody and mercury treatment decreases bone mineral density in mice.
Toxicol Appl Pharmacol 185: 98-110, 2002
- Kageyama A, Hirano T, Kageyama H, Osaka T, Namba Y, Tsuji M, Adachi M,
Inoue S: Distinct role of adiposity and insulin resistance in glucose
intolerance: studies in ventromedial hypothalamic-lesioned obese rats.
Metabolism 51: 716-23, 2002
- Kozaki K, Kaminski WE, Tang J, Hollenbach S, Lindahl P, Sullivan C, Yu
JC, Abe K, Martin PJ, Ross R, Betsholtz C, Giese NA, Raines EW: Blockade of
platelet-derived growth factor or its receptors transiently delays but does
not prevent fibrous cap formation in ApoE null mice. Am J Pathol 161:
1395-1407, 2002
- Kume H, Teramoto S, Isurugi K. In-vivo dedifferentiation of
keratinocytes to epidermal stem cells.Lancet 359: 528-529, 2002
- Kurosawa T, Hiroi H, Tsutsui O, Ishikawa T, Osuga Y, Fujiwara T, Inoue
S, Muramatsu M, Momoeda M, Taketani Y: The activity of bisphenol A depends
on both the estrogen receptor subtype and the cell type. Endocr J 49:
465-471, 2002
- Liang YQ, Akishita M, Kim S, Ako J, Hashimoto M, Iijima K, Ohike Y,
Watanabe T, Sudoh N, Toba K, Yoshizumi M, Ouchi Y: Estrogen receptor beta is
involved in the anorectic action of estrogen. Int J Obes Relat Metab Disord
26: 1103-1109, 2002
- Nagase T, Uozumi N, Ishii S, Kita Y, Yamamoto H, Ohga E, Ouchi Y,
Shimizu T: A pivotal role of cytosolic phospholipase A(2) in bleomycin-induced
pulmonary fibrosis. Nat Med 8: 480-484, 2002
- Nagase T, Ishii S, Shindou H, Ouchi Y, Shimizu T: Airway
hyperresponsiveness in transgenic mice overexpressing platelet activating
factor receptor is mediated by an atropine-sensitive pathway. Am J Respir
Crit Care Med 165: 200-205, 2002
- Ogawa S, Emi M, Shiraki M, Hosoi T, Orimo H, Ouchi Y, Inoue S:
Association of amino acid variation (Trp64Arg) in the beta3-adrenergic
receptor gene with bone mineral density. Geriatric Gerontol Int 2: 138-142,
2002
- Ogihara T, Morimoto S, Okaishi K, Hiwada K, Matsuoka H, Matsumoto M,
Takishita S, Shimamoto K, Shimada K, Abe I, Kohara K, Ouchi Y: Questionnaire
survey on the Japanese guidelines for treatment of hypertension in the
elderly: 1999 revised version. Hypertens Res 25: 69-75, 2002
- Otsuka M, Yamaguchi K, Ueki A: Similarities and differences between
Alzheimer's disease and vascular dementia from the viewpoint of nutrition.
Ann N Y Acad Sci 977: 155-161, 2002
- Sahara M, Inoue S, Sunaga S, Kitagawa H, Ako J, Hoshino S, Toba K, Ouchi
Y: Megakaryoblastic transformation of chronic myelomonocytic leukemia,
presenting with severe bone pain. Geriatric Gerontol Int 2: 105-109, 2002
- Sata M, Takahashi A, Tanaka K, Washida M, Ishizaka N, Ako J, Yoshizumi
M, Ouchi Y, Taniguchi T, Hirata Y, Yokoyama M, Nagai R, Walsh K: Mouse
genetic evidence that tranilast reduces smooth muscle cell hyperplasia via a
p21(WAF1)-dependent pathway. Arterioscler Thromb Vasc Biol 22: 1305-1309,
2002
- Sugiyama H, Ogawa S, Emi M, Shiraki M, Hosoi T, Orimo H, Ouchi Y, Inoue
S: Ethnic difference in contribution of alleles of the interleukin-1
receptor antagonist gene to preposition to osteoporosis. Geriatric Gerontol
Int 2: 87-90, 2002
- Teramoto S, Kume H, Ouchi Y. Altered Swallowing Physiology and
Aspiration in COPD. Chest 122: 1104-1105, 2002
- Teramoto S, Kume H, Ouchi Y: Nocturnal gastroesophageal reflux: symptom
of obstructive sleep apnea syndrome in association with impaired swallowing.
Chest 122: 2266-2267, 2002
- Teramoto S, Inoue Y, Ouchi Y: Clinical significance of sleep apnea
syndrome in the elderly. Geriatr Gerontol Int 2: 163-171, 2002
- Teramoto S, Ishii T, Matsuse T: Genetic susceptibility to tobacco smoke
toxicity and chronic obstructive pulmonary disease. Geriatr Gerontol Int 2:
1-7, 2002
- Teramoto S, Kume H, Matsuse T: Ambulatory blood pressure after sleep
apnoea treatment. Lancet 360: 341-342, 2002
- Teramoto S, Matsuse T, Fukuchi Y: Clinical significance of nocturnal
oximeter monitoring for detection of sleep apnea syndrome in the elderly.
Sleep Med 3: 67-71, 2002
- Tomita T, Nagase T, Ohga E, Yamaguchi Y, Yoshizumi M, Ouchi Y: Molecular
mechanisms underlying human beta-defensin-2 gene expression in a human
airway cell line (LC2/ad). Respirology 7: 305-310, 2002
- Urano T, Saito T, Tsukui T, Fujita M, Hosoi T, Muramatsu M, Ouchi Y,
Inoue S: Efp targets 14-3-3sigma for proteolysis and promotes breast tumour
growth. Nature 417: 871-875, 2002
- Yamaguchi Y, Nagase T, Makita R, Fukuhara S, Tomita T, Tominaga T,
Kurihara H, Ouchi Y: Identification of multiple novel epididymis-specific
beta-defensin isoforms in humans and mice. J Immunol 169: 2516-2523, 2002
- Ako J, Ikari Y, Hatori M, Hara K, Ouchi Y: Changing spectrum of
infective endocarditis: review of 194 episodes over 20 years. Circ J 67:
3-7, 2003
- Aoki T, Inoue S, Imamura H, Fukushima J, Takahashi S, Urano T, Hasegawa
K, Ogushi T, Ouchi Y, Makuuchi M: EBAG9/RCAS1 expression in hepatocellular
carcinoma: Correlation with tumour dedifferentiation and proliferation. Eur
J Cancer 39: 1552-1561, 2003
- Cosentino F, Eto M, De Paolis P, van der Loo B, Bachschmid M, Ullrich V,
Kouroedov A, Delli Gatti C, Joch H, Volpe M, Luscher TF: High glucose causes
upregulation of cyclooxygenase-2 and alters prostanoid profile in human
endothelial cells: role of protein kinase C and reactive oxygen species.
Circulation 107: 1017-1023, 2003
- Daida H, Ouchi Y, Saito Y, Yamada N, Nishide T, Mokuno H, Kurata T, Sato
H, Eto M, Ako J, Tango T, Yamaguchi H, Coronary Atherosclerosis and Lipid
Research Group: Preventing angiographic progression of coronary
atherosclerosis with pravastatin. J Atheroscler Thromb 10: 25-31, 2003
- Eto M, Toba K, Akishita M, Kozaki K, Watanabe T, Kim S, Hashimoto M,
Sudoh N, Yoshizumi M, Ouchi Y: Reduced endothelial vasomotor function and
enhanced neointimal formation after vascular injury in a rat model of blood
pressure lability. Hypertens Res 26: 991-998, 2003
- Eto M, Luscher TF: Modulation of coagulation and fibrinolytic pathways
by statins. Endothelium 10: 35-41, 2003
- Ezura Y, Nakajima T, Kajita M, Ishida R, Inoue S, Yoshida H, Suzuki T,
Shiraki M, Hosoi T, Orimo H, Emi M: Association of molecular variants,
haplotypes, and linkage disequilibrium within the human vitamin D-binding
protein (DBP) gene with postmenopausal bone mineral density. J Bone Miner
Res 18: 1642-1649, 2003
- Hoshino S, Hosoi T, Shiraki M, Orimo H, Ouchi Y, Inoue S: Association of
Tumor Necrosis Factor 1 (TNFR1) gene polymorphism with bone mineral density.
Geriatric Gerontol Int 3: 101-105, 2003
- Ishida R, Emi M, Ezura Y, Iwasaki H, Yoshida H, Suzuki T, Hosoi T, Inoue
S, Shiraki M, Ito H, Orimo H: Association of a haplotype (196Phe/532Ser) in
the interleukin-1-receptor-associated kinase (IRAK1) gene with low radial
bone mineral density in two independent populations. J Bone Miner Res 18:
419-423, 2003
- Ishida R, Ezura Y, Emi M, Kajita M, Yoshida H, Suzuki T, Hosoi T, Inoue
S, Shiraki M, Ito H, Orimo H: Association of a promoter haplotype
(-1542G/-525C) in the tumor necrosis factor receptor associated
factor-interacting protein gene with low bone mineral density in Japanese
women. Bone 33: 237-241, 2003
- Ishii T, Fujishiro M, Masuda M, Nakajima J, Teramoto S, Ouchi Y, Matsuse
T: Depletion of glutathione S-transferase P1 induces apoptosis in human lung
fibroblasts. Exp Lung Res 29: 523-536, 2003
- Iwasaki H, Emi M, Ezura Y, Ishida R, Kajita M, Kodaira M, Yoshida H,
Suzuki T, Hosoi T, Inoue S, Shiraki M, Swensen J, Orimo H: Association of a
Trp16Ser variation in the gonadotropin releasing hormone (GnRH) signal
peptide with bone mineral density, revealed by SNP-dependent PCR (Sd-PCR)
Typing. Bone 32: 185-190, 2003
- Jin GB, Nakayama H, Shmyhlo M, Inoue S, Kondo M, Ikezawa Z, Ouchi Y,
Cyong JC: High positive frequencies of antibodies to metallothionein and
heat shock protein 70 in sera of patients with metal allergy. Clin Exp
Immunol 131: 275-279, 2003
- Kajita M, Ezura Y, Iwasaki H, Ishida R, Yoshida H, Kodaira M, Suzuki T,
Hosoi T, Inoue S, Shiraki M, Orimo H, Emi M: Association of -381T/C promoter
cariation of brain natriuretic peptide gene with low bone mineral density
and rapid postmenopausal bone loss. J Hum Genet 48: 77-81, 2003
- Kageyama H, Osaka T, Kageyama T, Kawada T, Hirano T, Oka J, Miura M,
Namba Y, Ricquier D, Shioda S, Inoue S: Fasting increases gene expressions
of uncoupling proteins and peroxisome proliferator-activated receptor-gamma
in brown adipose tissue of ventromedial hypothalamus-lesioned rats. Life Sci
72: 3035-46, 2003
- Kageyama H, Kamegaya A, Endo Y, Osaka T, Nemoto K, Hirano T, Namba Y,
Shioda S, Inoue S: Ventromedial hypothalamus lesions induce jejunal
epithelial cell hyperplasia through an increase in gene expression of
cyclooxygenase. Int J Obes Relat Metab Disord 27: 1006-13, 2003
- Kanazawa M, Xue CY, Kageyama H, Suzuki E, Ito R, Namba Y, Osaka T,
Kimura S, Inoue S: Effects of a high-sucrose diet on body weight, plasma
triglycerides, and stress tolerance. Nutr Rev 61(5 Pt 2): S27-33, 2003
- Mizuno Y, Namba Y: Aging society and the adult guardianship system.
Geriatr Gerontol Int 3: 225-235, 2003
- Nagase T, Uozumi N, Aoki-Nagase T, Terawaki K, Ishii S, Tomita T,
Yamamoto H, Hashizume K, Ouchi Y, Shimizu T: A potent inhibitor of cytosolic
phospholipase A2, arachidonyl trifluoromethyl ketone, attenuates LPS-induced
lung injury in mice. Am J Physiol Lung Cell Mol Physiol 284: L720-726, 2003
- Nakamura T, Akishita M, Kozaki K, Toba K, Orimo H, Ouchi Y. Influence of
sex and estrogen on vitamin D-induced arterial calcification in rats.
Geriatric Gerontol Int 3: 145-149, 2003
- Ogihara T, Hiwada K, Morimoto S, Matsuoka H, Matsumoto M, Takishita S,
Shimamoto K, Shimada K, Abe I, Ouchi Y, Tsukiyama H, Katayama S, Imai Y,
Suzuki H, Kohara K, Okaishi K, Mikami H: Guidelines for treatment of
hypertension in the elderly--2002 revised version. Hypertens Res 26: 1-36
2003
- Ohga E, Tomita T, Wada H, Yamamoto H, Nagase T, Ouchi Y: Effects of
obstructive sleep apnea on circulating ICAM-1, IL-8, and MCP-1. J Appl
Physiol 94: 179-184, 2003
- Ohtoh T, Ono Y, Iwasaki Y, Sakurai Y, Nishino A, Arai H, Suzuki H, Namba
Y: Non-traumatic recurrent dissection and its spontaneous repair in the
circle of Willis: Report of two autopsy cases. Neuropathology 23: 195-198,
2003
- Okada S, Teramoto S, Takizawa H, Ouchi Y, Matsuoka R: Clinical
insignificance of (1-->3)-beta-D-glucan in early diagnosis of invasive
pulmonary aspergillosis in a patient with chronic obstructive pulmonary
disease. J Med Microbiol 52(Pt 11): 1031-1032, 2003
- Omasu F, Emi M, Ezura Y, Kajita M, Ishida R, Kodaira M, Yoshida H,
Suzuki, Hosoi T, Inoue S, Shiraki M, Orimo H: Association of genetic
variation of gene encoding LIM domain protein (RIL) with low bone mineral
density in postmenopausal Japanese women. J Hum Genet 48: 342-345, 2003
- Tabb MM, Sun A, Zhou C, Grun F, Errandi JL, Romero KM, Pham H, Inoue S,
Mallick S, Lin M, Forman BM, Blumberg B: Vitamin K2 regulation of bone
homeostasis is mediated by the steroid and xenobiotic receptor, SXR. J Biol
Chem 278: 43919-43927, 2003
- Takahashi S, Urano T, Tsuchiya F, Fujimura T, Kitamura T, Ouchi Y,
Muramatsu M, Inoue S: EBAG9/RCAS1 expression and its prognostic significance
in prostatic cancer. Int J Cancer 106: 310-315, 2003
- Teramoto S, Kume H, Ishii T, Mastsue T: Production of oxygen radicals by
peripheral blood neutrophils is increased in patients with stable asthma and
during exacerbations. Respiration 69: 286-287, 2003
- Teramoto S, Kume H, Matsuse T, Ishii T, Miyashita A, Akishita M, Toba K,
Ouchi Y: Oxygen administration improves the serum level of nitric oxide
metabolites in patients with obstructive sleep apnea syndrome. Sleep Med 4:
403-407, 2003
- Teramoto S, Kume H, Yamamoto H, Ishii T, Miyashita A, Matsuse T,
Akishita M, Toba K, Ouchi Y: Effects of oxygen administration on the
circulating vascular endothelial growth factor (VEGF) levels in patients
with obstructive sleep apnea syndrome. Intern Med 42: 681-685, 2003
- Teramoto S, Yamamoto H, Ouchi Y: Increased C-reactive protein and
increased plasma interleukin-6 may synergistically affect the progression of
coronary atherosclerosis in obstructive sleep apnea syndrome. Circulation
107: E40-0, 2003
- Teramoto S, Kume H, Matsuse T, Ishii T, Miyashita A, Akishita M, Toba K,
Ouchi Y: Oxygen administration improves the serum level of nitric oxide
metabolites in patients with obstructive sleep apnea syndrome. Sleep Med 4:
403-407, 2003
- Teramoto S, Yamamoto H, Ouchi Y: Clinical efficacy and toxicity of
gefitinib in patients with lung cancer. Lancet 361: 1992-1993, 2003
- Teramoto S, Yamamoto H, Yamaguchi Y, Kawaguchi H, Ouchi Y: Nosocomial
infections in adult intensive-care units. Lancet 362: 493, 2003
- Teramoto S, Yamamoto H, Yamaguchi Y, Matsuse T, Ouchi Y: Global burden
of COPD in Japan and Asia. Lancet 362: 1764-1765, 2003
- Tsurusaki T, Aoki D, Kanetake H, Inoue S, Muramatsu M, Hishikawa Y, Koji
T: Zone-dependent expression of estrogen receptor alpha and beta in human
benign prostatic hyperplasia. J Clin Endocrinol Metab 88: 1333-1340, 2003
- Watanabe T, Akishita M, He H, Miyahara Y, Nagano K, Nakaoka T, Yamashita
N, Kozaki K, Ouchi Y: 17 beta-estradiol inhibits cardiac fibroblast growth
through both subtypes of estrogen receptor. Biochem Biophys Res Commun 311:
454-459, 2003
- Watanabe T, Akishita M, Nakaoka T, Kozaki K, Miyahara Y, He H, Ohike Y,
Ogita T, Inoue S, Muramatsu M, Yamashita N, Ouchi Y: Estrogen receptor beta
mediates the inhibitory effect of estradiol on vascular smooth muscle cell
proliferation. Cardiovasc Res 59: 734-744, 2003
Annual Report of the Graduate School of Medicine and The Faculty of Medicine
The University of Tokyo Reports for the Period April 2002 - March 2004
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